NSF SBIR/STTR Scientific Instrumentation Pilot 2026

The U.S. National Science Foundation (NSF) SBIR/STTR Scientific Instrumentation Pilot 2026 invites startups and small businesses to develop next-generation scientific instrumentation, experimental platforms, and enabling technologies to advance scientific discovery. The program provides non-dilutive funding across multiple award mechanisms, with opportunities including Phase I, Phase II, Fast-Track, Phase IIB supplements, and Strategic Breakthrough Awards up to $30 million for exceptional projects.

Non-dilutive funding with potential for Phase I/II support and Strategic Breakthrough Awards up to $30 million, plus credibility and partnerships to attract future investment.

Visionary startups and small businesses capable of creating tools, equipment, and infrastructure to power future scientific breakthroughs.

Applications are accepted according to specified deadlines; an invitation via the NSF Project Pitch process is mandatory before submitting Phase I or Fast-Track proposals.